Women form the majority of Dr. Oz’s audience. The majority of women would want to shed weight. That is a match created in heaven, a marketer’s dream. And Oz has never hesitated to exploit this fact to enhance audience share, playing fast and loose with sensationalized evidence as an alternative to giving his viewers science-based advice.
Garcinia cambogia extract (GCE) arises from a tropical fruit from India and Southeast Asia. The active ingredient, pure garcinia cambogia extract, has been said to block fat and suppress the appetite.
Garcinia cambogia extract (GCE) originates from a tropical fruit from India and Southeast Asia. The active ingredient, hydroxycitric acid (HCA), has been said to bar fat and suppress the appetite.
Dr. Oz has promoted a series of weight loss supplements on his show. Raspberry ketones were presented being a fat-busting miracle, then green coffee bean extract was touted as “magic,” “staggering,” and “unprecedented.” And from now on each of those miracles have apparently been superseded by a much greater miracle: Garcinia cambogia extract.
Dr. Oz calls it “The newest, fastest fat buster.” A way to lose weight without “spending every waking moment exercising and dieting.” “Triples your weight loss.” “The most exciting breakthrough in natural fat loss up to now.” “The Holy Grail.” Oz claims that “Revolutionary new research says it may be the magic ingredient that allows you to lose weight without diet or exercise.”
All that sounds too good to be real, which is. Garcinia probably does work to some extent to boost weight loss, although the evidence doesn’t start to justify such grandiose claims.
Garcinia cambogia extract (GCE) arises from a tropical fruit grown in India and Southeast Asia. The active ingredient is identified: hydroxycitric acid (HCA). It is known to bar fat and suppress hunger. It inhibits a key enzyme, citrate lyase, the body needs to make fat from carbohydrates. It suppresses appetite by increasing serotonin levels; low serotonin levels are connected with depression and emotional or reactive eating.
It allegedly decreases abdominal fat, suppresses appetite, controls emotional eating, and changes body composition by increasing lean muscle mass. It doesn’t just produce weight reduction, but it really improves overall health. It is stated to diminish cholesterol, LDL, and triglycerides by 10-30% as well as raise amounts of the “good cholesterol” HDL.
An independent analysis found out that some brands contain a lot less active ingredient than claimed. Consumers should look for at least 50% GCE with potassium however with no fillers, binders, or artificial ingredients.
It ought to be taken on empty stomach 30-60 minutes before dinner. Results increase with dosage, but doses over 3 000 mg every day ought to be cleared with the doctor.
Dr. Oz recommends a dose of 500-1000 mg of pure garcinia cambogia weight loss before every meal. (Some experts believe the potassium salt is much more effective than other formulations.) He says to never carry it should you be pregnant or breastfeeding, or when you have Alzheimer’s disease or another forms of dementia, since it can worsen dementia. If you have diabetes, there may be hypoglycemia, and in case you are on a statin, it can increase the risk of harmful adverse reactions like rhabdomyolysis or muscle degradation.
Oz contradicts himself: he suggests that it will produce weight loss without diet or exercise, yet he clearly recommends it be applied in addition to exercise and properly portioned meals.
With Dr. Oz’s history, I found myself reluctant to simply accept his word for the wonders of Garcinia. I traveled to PubMed, wherein a search for hydroxycitric acid brought up 64 articles. Some were irrelevant, as well as the relevant ones included plenty of animal studies as well as a smaller variety of human studies with inconsistent results.
Guinea pigs over a high cholesterol diet who had been given another Garcinia species (atriviridis) had a tendency to decrease lipid composition levels and fat deposition inside the aorta. HCA caused congenital defects in rats. Another rat study found out that it decreased bodyweight gain and visceral fat accumulation by reducing intake of food but had no lasting beneficial effects on hypertriglyceridemia and hyperinsulinemia. One more rat study indicated that it suppressed excess fat accumulation but was toxic towards the testes.
To attempt to sound right of the inconsistent results, Onakpoya et al. did a systematic review of the published randomized controlled trials (RCTs) as of 2011. Their analysis found a tiny, statistically significant difference in fat loss (1.75 kg vs .88 kg, below 2 pounds). They commented that this studies all had methodological weaknesses, so these results could be on account of GIGO (garbage in/garbage out). Both studies with the best methodology found 84dexcpky statistically significant difference from placebo. Adverse events were two times as common with Garcinia (headache, nausea, upper respiratory and gastrointestinal symptoms). The authors concluded:
Evidence from RCTs suggests that Garcinia extracts/HCA generate fat loss about the temporary. However, the magnitude of the effect is small, is no longer statistically significant when only rigorous RCTs are considered, along with its clinical relevance seems questionable.
Oz featured the patient testimonial around the show coming from a woman who had lost 10 pounds in 4 months. She started noticing results right after a week; she reported that her sugar cravings were decreased, she had more energy, and she went down a gown size from 10 to 8. She had no unwanted effects. Says she was in a plateau and wanted a jump-start.
At this stage, I don’t think we could reliably say whether pure garcinia cambogia features a clinically relevant edge on simple calorie reduction and workout. It seems to be safe, and it also may have a role in assisting patients slim down by assisting motivation and enlisting placebo effects.
Dr. Oz’s popularity is enduring, but diet fads aren’t. I confidently expect another “miracle” to supplant Garcinia from the Land of Oz within the not-too-distant future.